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发育迟缓儿童体质的相关值:乌干达的一项横截面研究
Jack I Lewis1, Joseph Mbabazi2, Rolland Mutumba2
1Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
The Journal of nutrition
|August 7, 2024
概括
发育迟缓的儿童表现出身体组成的改变,炎症与生长不良和肥胖增加有关. 长时间的母乳养可能会支持瘦身的增长,但需要更多的研究.
科学领域:
- 儿科营养与生长 儿科营养与生长
- 身体组成分析 身体成分分析
- 儿童健康与发展
背景情况:
- 身体组成 (BC) 发育可能会受到阻碍,可能会增加未来肥胖和代谢问题的风险.
- 很少有研究探讨了在缩儿童中与BC相关的因素.
研究的目的:
- 为了研究营养状况,感染,炎症和母乳养行为,作为缩儿童的身体组成的相关因素.
- 在这个群体中确定影响脂肪质量 (FM) 和无脂肪质量 (FFM) 的因素.
主要方法:
- 生物电阻分析 (BIA) 用于估计750名乌干达儿童 (1-5岁) 的BC,其身高与年龄的z-score为<-2.
- 多重线性回归分析确定了FM,FFM,FM指数 (FMI) 和FFM指数 (FFMI) 的相关值,调整了性别和年龄,将结果与英国参考结果进行了比较.
主要成果:
- 与英国参考儿童相比,缩儿童的FMI和FFMIz分数较低.
- 炎症标志物 (α1-酸糖蛋白,C-反应蛋白) 的升高与线性生长和FFM的减少有关,但增加了FMI.
- 疟疾感染与较低的身高和更高的FMI有关,而贫血与较低的FFM有关.
- 较长的母乳养时间与FFM正相关,比例与身高.
结论:
- 发育迟缓的儿童相对于身高,在FM和FFM方面表现出缺陷.
- 系统性炎症是潜在的干预目标,它对线性生长和FFM产生反向影响,同时对肥胖产生积极影响.
- 长期母乳养可能有利于瘦身生长,尽管微量营养素的影响需要进一步研究.
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