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Updated: May 3, 2026

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诱导毛病病态和运动功能障碍在小鼠通过尿道外体从渐进性上核性患者的毛病病态和运动功能障碍

Qiusha Li1, Han Liu1, Qingyong Zhu1

  • 1Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Institute of Parkinson and Movement Disorder, Zhengzhou University, Zhengzhou, Henan 450052, China.

Brain research bulletin
|August 7, 2024
PubMed
概括

来自渐进性超核麻患者的尿液外体可以导致老鼠的病理和运动缺陷,这表明外体在PSP病变发生过程中发挥了作用.

关键词:
外基因组是外基因组的组成部分.细胞外囊泡中的细胞外囊泡.渐进性的超核性.塔乌·塔乌 (Tau Tau) 是一个尿液 尿液 尿液

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Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...
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