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Updated: Jun 17, 2025

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针对GRP78的小分子在培养内皮细胞中减轻了抗GRP78自身抗体介导的组织因子前凝剂活性

Jack Chen1, Edward G Lynn1, Hitesh Sharma1

  • 1Department of Medicine, Division of Nephrology, McMaster University, The Research Institute of St. Joe's Hamilton and The Hamilton Center for Kidney Research, Hamilton, Ontario, Canada.

Journal of thrombosis and haemostasis : JTH
|August 7, 2024
PubMed
概括

抗GRP78自身抗体会增加组织因子对内皮细胞的血凝活性,从而导致血栓形成. 新型GRP78结合剂显示出治疗动脉栓塞性疾病的潜力.

关键词:
在 Grp78 中使用.反GRP78的自身抗体.人工智能的人工智能是人工智能.动脉血栓形成的发生.细胞表面 GRP7878 细胞表面 GRP78

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