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Updated: Jun 17, 2025

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释放潜力:针对瘤微环境中的代谢途径进行癌症治疗

Siyuan Jia1, Ann M Bode2, Xue Chen3

  • 1Hunan Key Laboratory of Oncotarget Gene, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, PR China; Key Laboratory of Carcinogenesis and Invasion, Chinese Ministry of Education, Cancer Research Institute, School of Basic Medicine, Central South University, Changsha, Hunan 410078, PR China.

Biochimica et biophysica acta. Reviews on cancer
|August 7, 2024
PubMed
概括

癌细胞重新编程瘤微环境 (TME) 代谢,推动瘤生长和抵抗. 向癌症相关纤维细胞 (CAF),巨细胞 (TAM),淋巴细胞 (TIL) 和内皮细胞 (TEC) 的代谢途径提供了新的治疗策略.

关键词:
与癌症相关的纤维细胞 (CAFs).免疫检查点封锁 (ICB)代谢重编程是一种代谢重编程.瘤内皮细胞 (TECs) 是指瘤内皮细胞.瘤微环境 (TME) 是指瘤的微环境.与瘤相关的巨细胞 (TAMs)瘤透性淋巴细胞 (TILs) 治疗

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