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Updated: Jun 17, 2025

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
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Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

Published on: December 19, 2019

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EZH2 PROTACs针对EZH2和FOXM1相关的致癌节点,抑制乳腺癌细胞生长

Joshua Corbin1,2, Xufen Yu3,4, Jian Jin3,4

  • 1Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC, 27710, USA.

Oncogene
|August 7, 2024
PubMed
概括

向蛋白质溶解向仿真体 (PROTACs) 向增强器的向同类物2 (EZH2) 通过降解EZH2和FOXM1.1,有效地治疗抗他莫西芬乳腺癌. 这种方法显示出克服治疗耐药性的希望.

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