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Updated: Jul 31, 2026

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患者衍生性质瘤细胞系的多组和药理学表征

Min Wu1,2,3,4,5, Tingting Wang1,6,7, Nan Ji8,9

  • 1Chinese Institute for Brain Research, Beijing, Research Unit of Medical Neurobiology, Chinese Academy of Medical Sciences, Beijing, China.

Nature communications
|August 7, 2024
PubMed
概括

这项研究描述了50个来自患者的质瘤细胞系,确定了三种亚型 (介质细胞,脑前神经,氧化酸化),具有明显的药物敏感性和瘤形成能力. 长通道细胞的无血清培养揭示了MYC/MYCN放大,这是临床转化的一个关键问题.

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