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Updated: Jun 15, 2026

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51
06:24

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51

Published on: February 13, 2019

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在2.2 Å分辨率的人类全长RAD52的整合性结构研究

Beatrice Balboni1,2, Roberto Marotta3, Francesco Rinaldi1,2

  • 1Computational and Chemical Biology, Istituto Italiano di Tecnologia, Genoa, Italy.

Communications biology
|August 7, 2024
PubMed
概括

对人类RAD52 (RAD52) 的结构洞察力揭示了其作为抗癌标的潜力. 这项研究详细介绍了蛋白质的环状结构和柔性区域,这些区域对于DNA修复和药物开发至关重要.

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Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering07:19

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering

Published on: November 5, 2018

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Visualization of miniSOG Tagged DNA Repair Proteins in Combination with Electron Spectroscopic Imaging ESI13:06

Visualization of miniSOG Tagged DNA Repair Proteins in Combination with Electron Spectroscopic Imaging ESI

Published on: September 24, 2015

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相关概念视频

X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal crystal...