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细胞表面向免疫细胞因子的局部输送程序系统性抗瘤免疫力

Luciano Santollani1,2, Laura Maiorino2,3, Yiming J Zhang2,4

  • 1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Nature immunology
|August 7, 2024
PubMed
概括

通过局部治疗将CD45向interleukin-12和interleukin-15等细胞因子,安全地产生全身抗瘤免疫力. 这种新的方法通过重编程T细胞来根除瘤和远端病变.

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