早期儿童患儿慢性疼痛的风险因素:一项多方法纵向研究
Maria Pavlova1, Melanie Noel2,3,4, Serena L Orr3,4,5,6,7
1Department of Psychology, University of Guelph, Guelph, Canada.
BMC pediatrics
|August 7, 2024
概括
早期生活中的疼痛经历,如肠道问题和急诊室的访问,增加了儿科慢性疼痛的风险. 这些发现凸显了儿童早期查和干预的必要性.
科学领域:
- 儿科健康研究儿童健康研究
- 纵向队列研究是指纵向队列研究.
- 童年发展儿童的发展.
背景情况:
- 儿科慢性疼痛是一种影响儿童心理社会发展的普遍和致残的疾病.
- 它通常与心理健康问题同时发生,并且可以在没有事先受伤的情况下出现.
- 纵向研究对于了解慢性疼痛发作的早期风险因素至关重要.
研究的目的:
- 检查早期发育因素和儿科慢性疼痛发作之间的关联.
- 调查早期疼痛经历和心理健康症状的作用.
- 使用来自我们所有家庭 (AOF) 纵向怀孕队列的数据.
主要方法:
- 对从4个月到11岁的长度AOF数据的分析.
- 母婴自我报告的疼痛经历,慢性疼痛和心理健康症状.
- 适应性LASSO回归和多重归算 (MICE) 用于变量选择和分析.
主要成果:
- 早期的疼痛经历 (肠道问题,急诊,经常抱怨,头痛) 和女性性别与8岁时的慢性疼痛有关.
- 8岁的儿童慢性疼痛预测了11岁更高的疼痛频率和干扰.
- 男孩在11岁时报告了下部疼痛干扰.
结论:
- 一些早期的痛苦经历是儿童慢性疼痛的重要贡献者.
- 这些发现支持了对查和早期干预策略的需求.
- 进一步的研究应该探索慢性疼痛发展早期因素的复杂相互作用.
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