中国成年人血管衰老与认知功能之间的关联
Shi Chen1, Hao Zhang2, Jianan Zhang3
1Department of Nursing, the Second People's Hospital of Kunshan, Suzhou Vocational Health College, Suzhou, China.
BMC public health
|August 7, 2024
概括
高血压,特别是脉冲压 (PP),与中国成年人的认知功能较差有关. 压缩性血压升高 (SBP) 也与认知评分下降和损伤风险增加有关.
科学领域:
- 心血管健康 心血管健康
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 血管健康越来越被认为是影响认知功能的因素.
- 在中国人群中这种关联的现有证据有限.
- 这项研究调查了血管衰老和血压对中国认知的影响.
研究的目的:
- 为了检查动脉硬和血压与认知功能之间的关联.
- 评估与中国人群认知表现相关的血管衰老指标.
- 在这个人群中识别潜在的认知功能受损的预测因素.
主要方法:
- 利用了来自天宁队列 (N=5158) 的数据.
- 测量了动脉硬度 (大-大腿脉冲波速,脚-手腕指数) 和血压 (脉冲压,静脉压,透气压).
- 使用迷你精神状态检查 (MMSE) 评估认知功能,并使用回归分析.
主要成果:
- 较高的脉压 (PP) 与较低的MMSE得分和认知障碍风险增加有显著关联.
- 每个标准偏差的缩血压 (SBP) 增加与较低的MMSE得分和较高的损伤概率有关.
- 对于其他测量的血管参数,没有发现显著的关联.
结论:
- 血压,特别是脉冲压和缩血压,与中国成年人的认知功能有关.
- 脉压力成为认知功能受损的潜在预测因素.
- 研究结果强调了血管健康监测对于这一人口群体的认知健康的重要性.
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