选择性注意力功能障碍在艾滋病毒阴性患者早期形式的神经病
Caifeng He1, Tao Yuan1, Lili Yuan2
1Department of Dermatology, Yijishan Hospital of Wannan Medical College, Wuhu, 241000, Anhui, China.
European journal of medical research
|August 7, 2024
概括
早期神经 (NS) 损害了警报和定向注意力网络,与执行功能不同. 大脑MRI揭示了与HIV阴性患者的注意力缺陷相关的额头和胸膜异常.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 注意力网络测试 (ANT) 评估了警报,定位和执行注意力.
- 神经 (NS) 可以影响认知功能,包括注意力.
- 调查早期NS的注意力缺陷对于理解神经影响至关重要.
研究的目的:
- 为了评估早期神经 (NS) 的HIV阴性患者的注意力功能.
- 为了将注意力表现与大脑磁共振成像 (MRI) 发现在早期的NS相关联.
- 为了区分早期NS,没有NS的梅毒和健康对照之间的注意力网络性能.
主要方法:
- 招募了30名早期NS患者,31名非NS梅毒患者和35名健康对照 (所有艾滋病毒阴性).
- 进行了注意力网络测试 (ANT) 和迷你心理状态检查 (MMSE).
- 对NS和非NS组进行脑部MRI,以确定异常.
主要成果:
- 与非NS患者和对照人群相比,早期NS患者在定向和警报功能方面表现明显差.
- 在NS和非NS组之间没有观察到执行功能的显著差异.
- 在NS组中,脑MRI显示前额叶和/或 temporoparietal junction 的异常率更高.
结论:
- 早期神经与选择性注意力的显著缺陷有关,特别是在定向和警报功能方面.
- 这些注意力障碍与大脑的前额和顶部区域观察到的异常有关.
- 研究结果表明,在早期的NS中,注意力缺陷的潜在神经病理基础可能存在.
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