根据阶段和教育,丹麦的乳头甲状腺癌死亡率趋势
Sarah M Sørensen1, Christian Munk1, Thomas Maltesen2
1Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
Clinical endocrinology
|August 8, 2024
概括
在丹麦,从2000年到2015年,乳头甲状腺癌 (PTC) 的生存率有所改善,死亡率在所有阶段都下降. 局部PTC与中等教育和非局部PTC与中等或长期教育的下降最为显著.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 很少有研究研究了乳头甲状腺癌 (PTC) 存活率和死亡率的趋势.
- 社会经济地位,特别是教育水平,可能会影响这些趋势.
研究的目的:
- 分析PTC生存率和死亡率的趋势.
- 检查阶段,教育水平和PTC结果之间的关联.
主要方法:
- 全国范围的队列研究使用丹麦癌症登记处2000-2015年的数据.
- 评估五年全因死亡率和相对存活率.
- 分析五年死亡率和年平均百分比变化 (AAPC) 根据阶段和教育.
- 考克斯回归用于评估与PTC死亡率相关的因素.
主要成果:
- 总体而言,在所有阶段,PTC相对存活率增加,死亡率下降.
- 在受过中等教育的人群中,局部PTC死亡率下降 (AAPC = -7.0),但在受过长期教育的人群中增加 (AAPC = 19.8).
- 非局部化的PTC死亡率显示,在受过中等 (AAPC = -5.5) 和长期教育 (AAPC = -10.4) 的人群中,死亡率有下降趋势.
- 最近的诊断和高等教育与较低的PTC死亡率有关.
结论:
- 2000-2015年期间,丹麦的乳头甲状腺癌存活率有所改善,死亡率有所下降.
- 死亡率的最显著降低观察到的是具有中等教育程度的局部PTC和具有中等或长期教育程度的非局部PTC.
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