创伤后头痛和轻度创伤性脑损伤后抑郁症之间的关系
Marissa L Beal1, Kevin J Psoter1, Kathleen T Bechtold1
1Department of Psychiatry and Behavioral Health, Pennsylvania State University College of Medicine, Hershey (Beal); Department of Pediatrics (Psoter), Department of Physical Medicine and Rehabilitation (Bechtold), and Department of Psychiatry and Behavioral Sciences (Peters, Rao, Roy), Johns Hopkins University School of Medicine, Baltimore; Johns Hopkins University Krieger School of Arts and Sciences, Baltimore (Nagpaul); Neurological Diseases, BRAINBox Solutions, Richmond, Virginia (Van Meter); Department of Computational Medicine and Bioinformatics (Falk) and Department of Emergency Medicine (Korley), University of Michigan Medical School, Ann Arbor.
在轻度创伤性脑损伤 (mTBI) 后患有急性创伤后头痛 (PTH) 的患者,患有持续性PTH和抑郁症的风险更高. 早期PTH检测可以帮助识别需要对这些疾病进行监测的个体.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 创伤护理 创伤护理
背景情况:
- 轻度创伤性脑损伤 (mTBI) 可以导致持续的精神和体征症状.
- 创伤后头痛 (PTH) 和抑郁症是mTBI的常见后果.
- 急性PTH和后来的抑郁症状之间的关系需要进一步阐明.
研究的目的:
- 为了确定PTH和mTBI后抑郁症之间的关联.
- 确定受伤后立即存在的PTH是否预测未来最多6个月的抑郁症状.
主要方法:
- 对前HeadSMART研究数据的二次分析.
- 包括265名成年mTBI患者在急诊室进行评估.
- 使用了急性PTH (aPTH) 的Rivermead脑震荡后症状问卷和治疗抑郁症的患者健康问卷-9在基线和1,3,6个月.
主要成果:
- 在24小时内出现PTH的患者在1,3,6个月后更有可能出现PTH.
- 在所有随访点,急性PTH与更严重的抑郁症状和更高临床抑郁症的可能性有关.
- 持久的PTH和抑郁与最初的PTH存在有显著的相关性.
结论:
- 在mTBI24小时内发生的急性PTH是持续PTH和抑郁症状的预测因素.
- 紧急部门对aPTH的评估可以识别患有长期康复风险的患者.
- 建议在mTBI后对急性PTH患者进行PTH和抑郁症的监测.
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