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门诊血压表型,动脉硬和心脏重塑

Cesare Cuspidi¹, Rita Facchetti¹, Elisa Gherbesi²

¹Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

American journal of hypertension

|August 8, 2024

概括

动脉硬和左心室缩增加持续高血压的风险. 结合这些标志物可以改善一般人群中持续高血压的识别,帮助临床管理.

科学领域:

心血管医学心血管医学
高血压研究高血压研究
诊断生物标志物诊断生物标志物

背景情况:

有限的证据存在于动脉硬和左心室 (LV) 重塑/增高 (LVH) 与社区异常血压 (BP) 现型的关系.
这项研究调查了血管和心脏器官损伤与压力监测和心脏协会 (PAMELA) 研究队列中的血压表型之间的联系.

研究的目的:

评估动脉硬 (通过心脚血管指数 - CAVI测量) 和LV重塑/LVH与不同血压表型之间的关系.
确定联合血管和心脏器官损伤的增量值,以确定持续高血压 (SH).

主要方法:

对来自PAMELA研究的491名参与者的分析,随访10年和25年.
数据包括病史,人体测量,血液测试,办公室血压,门诊血压监测 (ABPM),心声学和CAVI测量.

主要成果:

患病率:持续的正常血压 (31.2%),白袍高血压 (10.0%),掩盖高血压 (24.2%),持续的高血压 (34.6%) 和不浸泡 (35.8%).
增加的CAVI和LV重塑/LVH与持续高血压的可能性增加了四倍 (OR=4.31).
结合的标记物显示在区分SH与单独的标记物相比,具有增量价值.

结论:

血管和心脏目标器官损伤对于优化持续高血压的识别是有价值的.
这种方法可以提高在一般人群中持续高血压的临床管理.

关键词:

卡维 (Cavi) 是一个古老的城市.动脉硬性动脉硬性血压血压血压血压这种高血压,高血压.左心室缩症是指左心室缩症.左心室重塑的左心室重塑持续的高血压持续的高血压.

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