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非增强型计算机断层扫描作为疑似肺高血压的诊断工具:一项回顾性横截面试点研究
Ze Ming Goh1, Christopher S Johns2, Tarik Julius2
1Department of Infection Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, S10 2RX, UK.
主肺动脉直径和右心房区域的无增强CT测量显示出用于诊断肺高血压 (PH) 的高准确性和可重复性. 三状环形直径对于PH诊断来说不那么可靠.
科学领域:
- 放射学 放射学是一门学科.
- 心血管成像 - 心血管成像
- 肺部医学 肺部医学
背景情况:
- 计算机断层扫描肺血管造影 (CTPA) 用于肺高血压 (PH) 的诊断.
- 对PH的无增强CT测量的诊断实用性需要进一步评估.
研究的目的:
- 评估心脏和大血管参数的诊断实用性和可重现性,使用未增强的CT在疑似PH的患者中.
主要方法:
- 42名疑似PH的患者接受了无增强CT和右心脏导管 (RHC).
- 三名观察员在没有增强的CT上测量了心脏和大血管的参数.
- 用AUC评估诊断的准确性;观察者之间的变异性由ICC确定.
主要成果:
- 主肺动脉 (MPA) 的直径显示了最高的精度 (AUC 0.79-0.87) 和可重复性 (ICC 0.96,0.92).
- 右心房区域显示高精度 (AUC 0.76-0.79) 和可重现性 (ICC 0.980,0.950).
- 三管环直径的诊断可靠性较低.
结论:
- MPA直径和右心房区域是可复制和准确的非增强型CT测量,用于PH诊断.
- 这些参数在评估PH时可能具有临床价值.
- 由于可靠性较低,不建议在PH诊断中使用三环直径.
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