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饮食中的蛋白质,氨基酸和2型糖尿病:简要回顾
1Division of Human Nutrition and Health, Chair Group Nutritional Biology, Wageningen University & Research, Wageningen, Netherlands.
Frontiers in nutrition
|August 8, 2024
概括
摄入高蛋白质的高摄入量
科学领域:
- 营养科学 营养科学
- 代谢障碍 代谢障碍 代谢障碍
- 内分泌学 在内分泌学.
背景情况:
- 糖尿病是一种全球代谢障碍,其特点是胰岛素抵抗和胰岛素分泌受损.
- 可修改的生活方式因素,包括饮食,体力活动和体重,在预防糖尿病方面至关重要.
- 高蛋白质消费因其与糖尿病风险和管理的复杂关系而受到探索.
研究的目的:
- 审查当前对增加饮食蛋白质,氨基酸和2型糖尿病之间的关系的理解.
- 探索饮食蛋白质对胰岛素抵抗和葡萄糖平衡的影响.
- 为2型糖尿病患者提供蛋白质建议.
主要方法:
- 本综述综合了观察和干预研究的发现.
- 它检查了分支链氨基酸 (BCAA) 在心脏代谢风险中的作用.
- 该评论讨论了蛋白质和氨基酸对葡萄糖代谢的生理影响.
主要成果:
- 观察性研究将高总和动物蛋白摄入量与2型糖尿病风险的增加联系起来,特别是在肥胖女性中.
- 升高的BCAA与心脏代谢风险增加和胰岛素抵抗有关.
- 干预研究表明,高蛋白饮食有助于减肥,改善心脏代谢因素,但对胰岛素敏感性的影响是复杂的.
结论:
- 饮食蛋白质和2型糖尿病之间的关系是多方面的,有风险和潜在的好处.
- 分链氨基酸在胰岛素抵抗和心脏代谢风险方面发挥着重要作用.
- 需要进一步的研究来澄清高蛋白摄入量对葡萄糖平衡的长期影响,并为糖尿病管理制定最佳蛋白质建议.
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