尿液中含量与胆结石风险之间的相关性:高摄入量与胆结石发生有关
Yunfan Li1, Minchen Wang1, Wenyi Du2
1Department of General Surgery, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Frontiers in nutrition
|August 8, 2024
概括
这项研究发现,尿液中较高的含量与胆结石风险增加之间存在联系. 这表明过多的摄入可能会导致胆结石形成.
科学领域:
- 微量元素的新陈代谢
- 人类健康与营养
- 流行病学 流行病学
背景情况:
- 微量元素对人类发育至关重要,但过量摄入可能是有害的.
- 之前没有研究过胆结石与尿液中,和的度之间的关联.
研究的目的:
- 调查尿液中,和含量与美国人口中的胆结石发生之间的相关性.
- 为了确定过多的摄入是否与胆结石的发展有关.
主要方法:
- 分析了来自2,734名参与者的数据 (2017-2020年).
- 使用感应合血质谱法 (ICP-MS) 量化尿,和.
- 胆结石的存在通过标准化问卷进行评估;统计分析包括受限制的立方线,子组和后勤回归.
主要成果:
- 后勤回归显示,在尿四分位数较高的情况下,胆结石发病风险增加.
- 限制性立方脊线分析显示,尿液中含量与胆结石发育之间存在非线性正相关性 (P-非线性=0.032).
- 亚组分析表明,高尿水平与老年人 (≥60岁),女性,BMI≥25个体和糖尿病患者的胆结石风险更高有关.
结论:
- 在尿液中水平升高和胆结石风险增加之间存在显著的相关性.
- 尿液中的水平反映了的状态,这表明过度摄入可能会增加胆结石形成的风险.
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