评估80岁以上结肠癌患者的手术结果和生存率
Ana Sofia Cavadas1, Jorge Rodrigues2, Carlos Costa-Pereira1
1General Surgery Department, Hospital de Braga, Braga, PRT.
Cureus
|August 8, 2024
概括
选择性,治疗意图的手术显著改善了80岁以上的老年结肠癌患者的生存率. 突发性手术与较差的结果有关,突出显示了在这个人群中需要量身定制的护理策略.
科学领域:
- 老年人手术是一门老年手术.
- 手术瘤学手术瘤学
- 结肠直肠癌研究研究
背景情况:
- 全球人口老龄化需要了解结肠癌老年患者的手术结果.
- 优化结肠癌老年人的治疗策略对于改善生存率至关重要.
研究的目的:
- 为了分析80岁及以上的结肠癌手术患者的手术结果和生存率.
- 在这个人口群体中,比较选择性和新兴手术方法之间的结果.
主要方法:
- 在2018年至2021年期间,对90名80岁以上被诊断患有结肠癌的患者进行了观察性回顾性纵向研究.
- 人口和临床特征的表征,包括东部合作瘤组 (ECOG) 的绩效状况和查尔森并发症指数.
- 卡普兰-梅尔方法用于生存分析,根据手术意图 (治愈性与息性) 和入院类型 (选择性与突发性) 的结果进行比较.
主要成果:
- 有治愈意图的选择性手术 (73%) (80%) 是常见的,在66.7%的病例中使用了腹腔镜方法.
- 紧急入院与晚期癌症相相关,有较高的息治疗程序率,以及增加的开放性手术.
- 选择性 (36.7个月) 与新兴 (11.9个月) 住院的平均整体存活时间显著更好,以及治疗意图 (39.8个月) 与息性 (10.6个月) 手术的平均整体存活时间.
结论:
- 选择性,治疗意图的手术对于优化老年结肠癌患者的整体存活率至关重要.
- 尽管存在复杂性,但定制的术后管理和治疗策略对于改善这一年龄组的结果至关重要.
- 新出现的手术病例具有更高的复杂性和更低的生存率,这强调了及时选择性干预的重要性.
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