前脊髓梗塞:一个罕见的诊断与一个不常见的呈现
Sílvia Ferreira1, Angelo Fonseca2, Filipe Correia2
1Intensive Care Unit, Hospital Pedro Hispano, Matosinhos, PRT.
Cureus
|August 8, 2024
概括
脊髓梗塞 (SCI) 是一种罕见的中风类型. 这一案例突出了严重的高甘油三血症诱导的SCI,强调了诊断挑战和特征性的MRI发现,如"猫头".
科学领域:
- 神经学 神经学
- 血管神经学 血管神经学
- 放射学 放射学是一门学科.
背景情况:
- 脊髓梗塞 (SCI) 是一种罕见的血管事件,占所有中风的1%,呈现出各种神经系统综合征.
- 由于发病,严重程度和恢复模式各不相同,诊断是具有挑战性的,这取决于临床表现和MRI确认.
- 风险因素包括肥胖,高尿血,血脂不良和吸烟,正如这位患者所见的那样.
研究的目的:
- 报告一种罕见的脊髓梗塞 (SCI) 病例,与严重的高甘油三血相关.
- 要突出特征性的MRI发现,包括"猫头的眼睛"的标志,在前脊髓动脉 (ASA) 梗塞.
- 强调SCI的诊断挑战和不同的病因.
主要方法:
- 一个72岁的男性突然的临床病例介绍.
- 诊断工作包括神经学检查,实验室测试 (揭示高甘油三血症) 和MRI.
- 核磁共振扫描结果证实了ASA中的急性缺血性病变,具有特征的"猫头眼"标志.
主要成果:
- 患者表现为胸痛,进展为残肢和T6以下的感觉丧失.
- 严重的高甘油三血症被确定为潜在的促成因素.
- 核磁共振扫描 (MRI) 在ASA中证实SCI具有"猫头的眼睛"标志,尽管最初的临床表现不一致,归因于临床胀.
结论:
- 脊髓梗塞是 paraplegia的不常见原因,需要高度的临床怀疑.
- 严重的高甘油三血症可能是SCI的罕见病因.
- 典型的MRI发现有助于诊断SCI,强调考虑不同的病因的重要性.
相关概念视频
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Transient Ischemic Attack l: Introduction
A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...


