在患有肌肉衰弱的青春期后由于末端膜紧张而表现出肌肉衰弱的患者的外科结局
Takaki Kitamura1,2, Yasuaki Murata3, Tomonori Shigemura3
1Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, JPN.
Cureus
|August 8, 2024
概括
解锁手术有效地改善了青少年和成年患者的肌肉软弱和疼痛,这些患者的 filum terminale 紧张. 这种干预也解决了大多数情况下的肠和膀功能障碍,提供了显著的症状缓解.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 整形外科 整形外科 整形外科
背景情况:
- 紧张性末端 (TFT) 是一种先天性神经疾病,常常表现出各种症状,包括渐进的肌肉衰弱.
- 关于青少年和成人TFT相关肌肉衰弱的文献有限,这给诊断和治疗带来了挑战.
- 在TFT中放射性发现往往是微妙的,使诊断复杂化,并强调需要临床评估.
研究的目的:
- 评估手术解锁在改善TFT后青少年患者肌肉衰弱和相关症状的疗效.
- 评估解锁对疼痛和肠/膀功能障碍在这个患者队列中的影响.
主要方法:
- 对七名患有TFT和肌肉衰弱的青春期后患者进行了回顾性分析,这些患者接受了手术解锁.
- 在手术后,对患者的结果进行了监测,以检查肌肉强度,疼痛和肠道和膀功能障碍 (BBD) 的改善.
主要成果:
- 所有患者在脱后肌肉疲软显著改善,平均9.1周内恢复.
- 以前非行走的患者在平均22.3周内恢复了独立的运动能力.
- 疼痛和BBD也显著改善,在七名患者中,六名患者的BBD有所缓解.
结论:
- 手术解是一种高度有效的治疗肌肉衰弱和相关症状在后青春期患者诊断出紧张的 filum terminale.
- 该程序为疼痛和肠/膀功能障碍提供了实质性的好处,改善了整体生活质量.
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