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来自受压力的β细胞的细胞外囊泡调解单细胞激活,并导致岛屿炎症

Mette C Dekkers1, Joost M Lambooij1,2, Xudong Pu1

  • 1Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.

Frontiers in immunology
|August 8, 2024
PubMed
概括

受到压力的β细胞释放出细胞外囊泡 (EVs),在1型糖尿病 (T1D) 中促进炎症. 这些携带特定微RNA的EV激活免疫细胞,导致岛屿破坏和T1D进展.

关键词:
他们的压力是压力.细胞外囊泡中的细胞外囊泡.这是一种炎症炎症炎症炎症.单细胞 (Monocytes) 是一种单细胞.第1类糖尿病 1型糖尿病

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