中国多学科专家共识 免疫检查点 基于抑制剂的肝细胞癌组合疗法 (2023年版)
Xiufeng Liu1, Yinying Lu2, Weiping Zhou3
1Department of Medical Oncology of PLA Cancer Center, Jinling Hospital, Nanjing, China.
Liver cancer
|August 8, 2024
概括
肝细胞癌 (HCC) 治疗现在严重依赖免疫检查点抑制剂 (ICI) 组合疗法. 这份最新的共识为这些先进免疫疗法的合理,有效和安全的临床应用提供了专家指导.
科学领域:
- 肝胆道癌症 肝胆道癌症
- 免疫治疗是一种免疫疗法.
- 在瘤学瘤学.
背景情况:
- 免疫检查点抑制剂 (ICI) 联合疗法是不可切除的肝细胞癌 (HCC) 的基石.
- 在临床试验和实践中已经证明了显著的疗效.
研究的目的:
- 为合理,有效和安全地使用基于ICI的组合疗法在HCC中提供最新的临床指导.
- 帮助临床医生应用最新的研究和专家经验.
主要方法:
- 召开了一个多学科专家讨论会.
- 采用了德尔菲共识形成方法.
- 该共识从2021年版进行了修订和更新.
主要成果:
- 共识侧重于ICI组合疗法的临床实践的原则和方法.
- 总结了临床应用的建议.
- 为临床医生提供的指导是基于最新的证据.
结论:
- 这种共识是临床医生用组合免疫疗法管理HCC的重要资源.
- 它旨在通过基于证据和专家信息的建议来优化患者的治疗结果.
相关概念视频
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Tumor Immunotherapy
497
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
497
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K


