全球基因治疗临床试验到2023年 - - 一个更新
Samantha L Ginn1, Mawj Mandwie1, Ian E Alexander1,2
1Gene Therapy Research Unit, Children's Medical Research Institute, The University of Sydney and The Sydney Children's Hospitals Network, Westmead, NSW, Australia.
The journal of gene medicine
|August 8, 2024
概括
全球基因疗法临床试验已达到3900个,覆盖46个国家. 本综述分析了试验分布,疾病点,载体使用和基因转移,突出了快速增长和基因组编辑的进步.
科学领域:
- 生物技术是生物技术.
- 遗传学 遗传学 是一个
- 临床研究 临床研究
背景情况:
- 基因疗法在全球范围内取得了显著的发展.
- 对基因疗法临床试验的全面数据库对于跟踪进展至关重要.
研究的目的:
- 分析全球基因疗法临床试验.
- 确定基因治疗研究和开发的趋势.
主要方法:
- 从全球试验数据库,官方来源,文献以及调查员/赞助商提交的文件中编制的数据.
- 分析了试验的地理分布,疾病征兆,载体类型和基因标.
- 截至2023年3月,更新的数据库包含46个国家的3900项试验.
主要成果:
- 3,900个基因疗法临床试验已经完成,正在进行,或在全球获得批准.
- 分析涵盖了地理分布,疾病征兆,载体利用和基因转移.
- 观察到基因治疗试验活动的显著增加,包括基因组编辑技术.
结论:
- 基因疗法临床试验活动正在全球迅速扩大.
- 基因组编辑技术正在成为该领域的变革性工具.
- 综合数据库为全球基因治疗研究提供了有价值的见解.
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