婴儿的母乳养模式与以后的自闭症谱系障碍诊断有关
Leena Elbedour1, Rewaa Balaum1, Einav Alhozyel1
1Department of Epidemiology, Biostatistics and Community Health Sciences, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
概括
超过12个月的纯母乳养与较低的自闭症谱系障碍 (ASD) 几率有关. 六个月后早期引入固体食物可能会增加自闭症的可能性,强调婴儿营养对神经发育的重要性.
科学领域:
- 儿科 儿科 儿科
- 神经发育障碍 神经发育障碍
- 营养科学 营养科学
背景情况:
- 哺乳为婴儿提供了显著的医疗和发育优势.
- 自闭症谱系障碍 (ASD) 是一种复杂的神经发育状况,患病率越来越高.
- 早期的营养是影响婴儿发育和长期健康结果的关键因素.
研究的目的:
- 调查婴儿生命第一年的营养模式与自闭症谱系障碍 (ASD) 风险之间的联系.
- 为了确定母乳养的持续时间和固体食品的引入时间是否与ASD诊断相关.
- 提供基于证据的见解,了解早期营养在神经发育轨迹中的作用.
主要方法:
- 追溯病例控制研究设计.
- 包括270名被诊断为ASD的儿童 (病例) 和500名匹配的神经类型对照.
- 从母婴健康诊所收集的数据,使用条件逻辑回归调整混因子进行分析.
主要成果:
- 纯母乳养和部分母乳养都与ASD诊断的几率显著降低有关.
- 超过12个月的母乳养时间显示,ASD的可能性显著降低.
- 六个月后引入固体食物与与六个月后引入相比,与ASD的几率增加有关.
结论:
- 长期纯母乳养与随后的ASD诊断的可能性降低有关.
- 这些发现强调了适当的产后营养在支持健康婴儿神经发育方面的关键作用.
- 优化婴儿养实践可能有助于减轻自闭症风险.
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