对TGF-β激活的Smad复合物的DNA结合特性分析揭示了细胞上下文依赖信号传递的可能分子基础

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Updated: Jun 17, 2025

Analysis of the c-KIT Ligand Promoter Using Chromatin Immunoprecipitation
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Yuka Itoh1, Kunio Miyake2, Daizo Koinuma3

  • 1Department of Biochemistry, Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|August 8, 2024
PubMed
概括

转化生长因子-β (TGF-β) 信号调节基因表达. 这项研究使用CAST来发现由Smad复合体结合的DNA序列,揭示细胞特异性结合,并确定参与TGF-β反应的新动机.

关键词:
这是一个可悲的悲伤.在TGF-ββ.取决于环境的信号传输.

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