在连续注射血小板丰富血 (PRP) 后的潜在结果在声伤痕和硫中
Chloe Santa Maria1, Elizabeth A Shuman1, Benjamin Van Der Woerd2
1USC Voice Center, Caruso Department of Otolaryngology, Head and Neck Surgery, Keck School of Medicine, Los Angeles, California, U.S.A.
The Laryngoscope
|August 8, 2024
概括
富血小板血 (PRP) 注射为声痕提供了安全的治疗方法,改善了患者报告的结果和语音质量. 虽然结果各不相同,但PRP显示了声再生和功能恢复的潜力.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 再生医学是一种再生医学.
- 声带生理学 声带生理学
背景情况:
- 由于缺乏最佳的治疗方法,声的痕和硫会带来重大治疗挑战.
- 富于血小板的血 (PRP),是一种自身生长因子的度,显示出对表面膜自身再生的希望.
- 目前对声痕的治疗选择有限,需要探索新的再生方法.
研究的目的:
- 评估连续的富血小板血 (PRP) 注射在恢复声中的粘膜波功能方面的疗效.
- 评估PRP注射对声部整体功能的影响以及声痕症患者患者报告的结果.
- 确定PRP的安全性和潜在益处,作为声痕的再生治疗方法.
主要方法:
- 一项前性临床试验,涉及两个机构的15名声伤痕患者.
- 患者接受了四次连续的富血小板血 (PRP) 注射,分隔一个月.
- 盲人喉科医生和专家听众评估了视频强管镜,CAPE-V分数以及患者报告的治疗前后结果 (PROMs).
主要成果:
- 15名患者接受了55次PRP注射,没有报告任何不良反应,证实了安全性.
- 在患者报告的结果指标中观察到显著改善,VHI-10得分平均减少8.7分 (p=0.007).
- 评级人员在73.4%的病例中注意到语音质量的改善,平均CAPE-V分数下降了18.8分 (p=0.036),视频斯特罗博斯科普粘膜波评级有所改善.
结论:
- 富血小板血 (PRP) 已被验证为一种安全的,自主治疗方案,用于声痕.
- 虽然粘膜波和语音质量的改善显示出变化,但观察到患者报告结果的持续改善.
- 连续注射PRP代表了一种有前途的治疗策略,用于管理声的痕和改善声功能.
关键词:
富于血小板血的血含量是多少声 (Sulcus Vocalis) 是一个声 (Sulcus Vocalis) 是一个声 (Vocalis).表面的拉米纳自身缺陷.声音折叠的痕 在声音折叠的痕.发声的声音 (sulcus sulcus) 是一种声音.更多相关视频
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