巨型腹细胞的发病率:预测因素和管理策略
Laura Martou1, Amulya K Saxena1
1Department of Paediatric Surgery, Chelsea Children's Hospital, Chelsea and Westminster NHS Foundation trust, Imperial College London, London, UK.
Acta paediatrica (Oslo, Norway : 1992)
|August 8, 2024
概括
预测胃病 (GO) 结果不佳的预测因素包括额外的先天性异常,更大的缺陷大小,肝脏,和肺高血压. 这些因素对于识别患病风险较高的婴儿至关重要.
科学领域:
- 儿科手术 儿科手术
- 新生儿医学 新生儿医学
- 遗传异常是一种先天性异常.
背景情况:
- 胃 (GO) 是一种先天性腹壁缺陷,结果各不相同.
- 确定发病率预测因素对于优化患者管理和提高生存率至关重要.
研究的目的:
- 为了确定患有胃 (GO) 的新生儿患病率的预测因素.
- 分析相关异常,缺陷特征和管理策略与患者结果的关联.
主要方法:
- 从2013年到2023年,在PubMed和Ovid EMBASE上进行了系统的文献搜索.
- 主要终点包括患病率与妊娠年龄的相关性,出生体重,切除器官,缺陷大小,相关异常和管理策略.
主要成果:
- 对1009例GO病例的分析显示,发病率与肺高血压/低血,主要先天性异常,更大的缺陷大小和肝脏沟之间存在显著联系.
- 常见的并发症包括败血症,呼吸道损害和食功能障碍,以及长期的疾病,如家庭通风和神经发育延迟.
- 管理策略包括初级关闭,分阶段关闭或保守治疗,并发症率各不相同.
结论:
- 存在额外的先天性异常,更大的缺陷大小,肝和肺高血压/低血是胃病不良结果的关键预测因素.
- 这些预测因素的早期识别可以指导手术和医疗干预,以改善新生儿的结果.
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