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Updated: Jun 17, 2025

Preparation of Nucleosome Core Particles Complexed with DNA Repair Factors for Cryo-Electron Microscopy Structural Determination
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一个对DNA损伤反应H3K4me3结合WDR76:SPIN1复合体与核酶体的综合结构模型

Xingyu Liu1, Ying Zhang1, Zhihui Wen1

  • 1Stowers Institute for Medical Research, Kansas City, MO 64110.

Proceedings of the National Academy of Sciences of the United States of America
|August 8, 2024
PubMed
概括

研究人员使用连续捕获亲和力净化 (SCAP) 来研究WDR76:SPIN1蛋白质复合体,揭示了它在DNA损伤反应中的作用以及它与基因组上表观遗传标记的相互作用.

关键词:
在这种情况下,染色染色素交叉链接质谱仪的质谱仪.综合结构建模 综合结构建模蛋白质组学 蛋白质组学

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