具有相似功能的不同基因构成了Myotis蝙蝠生态形态的融合进化的基础
Ariadna E Morales1,2,3,4,5, Frank T Burbrink2, Marion Segall2,6,7
1Department of Mammalogy, Division of Vertebrate Zoology, American Museum of Natural History, New York, USA.
Molecular biology and evolution
|August 8, 2024
概括
蝙蝠的融合进化表明,类似的环境可以推动可预测的基因组变化. 这些变化会影响感官感知,发育和新陈代谢,即使涉及不同的基因.
科学领域:
- 进化生物学 进化生物学
- 基因组学就是基因组学.
- 哺乳动物进化 哺乳动物进化
背景情况:
- 融合进化允许研究进化轨迹中的可预测性.
- 蝙蝠属Myotis提供了由于寻策略的独立进化的融合进化的模型.
研究的目的:
- 为了研究Myotis蝙蝠融合进化的基因组基础.
- 识别与不同生物地理区域的生态形态融合相关的功能性基因组变化.
主要方法:
- 17个新的蝙蝠基因组的测序和注释.
- 选 16,426 个基因以检测积极选择和进化速率的关联.
- 在30种Myotis物种中进行了比较分析,这些物种代表了不同的食策略和地理来源.
主要成果:
- 确定了与遗传学史和生态形态学趋势相关的基因组变化.
- 在环境殖民期间推断出一系列的遗传变化:听力,然后生育/发育,新陈代谢和血红素降解.
- 观察到类似形式 (ecomorphs) 的重复进化可以涉及具有相似分子功能的不同基因.
结论:
- Myotis蝙蝠的融合进化与涉及感官感知,发育和新陈代谢的特定基因组有关.
- 这项研究强调了环境压力如何在基因组层面上塑造可预测的进化途径.
- 功能融合,而不是严格的基因保护,似乎驱动了蝙蝠的重复生态态进化.
相关概念视频
Convergent Evolution
27.6K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
27.6K
Multi-species Conserved Sequences
3.9K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.9K
Synteny and Evolution
3.2K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
3.2K
Gene Evolution - Fast or Slow?
7.1K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
7.1K
Gene Duplication and Divergence
6.1K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
6.1K
Gene Families
8.8K
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
8.8K


