在内透膜外科手术期间状鼻的解剖学差异:非功能性垂体神经内分泌瘤 (PiTNET) 和分泌生长激素的PiTNET之间的比较
Enrico Lo Bue1, Alessandro Pesaresi1, Paola Lacroce2
1Department of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy; Skull Base and Pituitary Surgery Unit, "Città della Salute e della Scienza" University Hospital, Turin, Italy.
World neurosurgery
|August 8, 2024
概括
增长激素分泌的垂体神经内分泌瘤 (GH分泌PitNET) 患者有较窄的状鼻,增加了手术的复杂性. 术前规划对于这些患者的安全内镜内腔方法至关重要.
科学领域:
- 神经外科 神经外科
- 内分泌学 在内分泌学.
- 人体解剖学 解剖学 解剖学
背景情况:
- 患有GH分泌PitNET的患者在内镜内外科手术期间呈现出独特的解剖变异.
- 这些变异包括更窄的鼻腔和鼻腔,可能增加手术复杂性和并发症风险.
- 了解这些差异对于手术规划至关重要.
研究的目的:
- 为了比较GH分泌PitNET和非功能PitNET (NF-PitNET) 患者之间的状鼻解剖学.
- 为了评估与内镜内道方法相关的解剖学差异.
- 确定在GH分泌PitNET病例中导致手术复杂性的因素.
主要方法:
- 对100名接受内镜内鼻治疗的患者进行了回顾性单心研究.
- 测量包括最小的关节间距离,状鼻 (DSS) 的最大直径,以及吐器 - 骨间距离 (VCD).
- 评估膜间隔膜隔膜的存在,定位和过程.
主要成果:
- 与NF-PitNET组相比,GH分泌的PITNET组显示出显著较小的骨间距离 (16.8毫米与20.4毫米),DSS (32.5毫米与38.6毫米) 和VCD (25.5毫米与29.6毫米).
- 这些发现表明,在患有GH分泌PitNET.NET的患者中,手术领域更为狭窄.
- 两组之间没有观察到膜间隔膜隔膜的显著差异.
结论:
- 患有GH分泌PitNET的患者表现出较小的关节间距离,DSS和VCD,证实了更狭窄的外科领域.
- 精心的手术前解剖规划和神经导航对于识别形骨标志至关重要.
- 这些措施对于降低手术风险至关重要,特别是在肌病患者中.
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