介绍介绍介绍介绍

Randy Q Cron¹, Edward M Behrens²

¹University of Alabama at Birmingham, Birmingham, AL, USA. randycron@uabmc.edu.

Advances in experimental medicine and biology

|August 8, 2024

概括

COVID-19大流行突出了细胞因子风暴综合征 (CSS),并导致发现了新的免疫相关疾病,如儿童多系统炎症疾病 (MISC). 这强调了对CSS的最新知识的需要.

科学领域:

免疫学免疫学免疫学
传染性疾病传染性疾病
儿科儿科儿科

背景情况:

随着COVID-19大流行,细胞因子风暴综合征 (CSS) 引起了公众和科学家的注意.
新的免疫媒介疾病的出现,如儿童多系统炎症性疾病 (MISC),与大流行相吻合.
细胞因子是已建立和新发现的CSSs病理学的核心.

研究的目的:

根据最近的科学进展,提供关于细胞因子风暴综合征 (CSSs) 的最新概述.
纳入对CSSs相关的免疫反应和病理学的新理解.
为了解决在COVID-19流行病和MISC描述后修订信息的需要.

主要方法:

审查最近的科学文献和与细胞因子风暴综合征相关的临床观察.
分析细胞因子在COVID-19和儿童多系统炎症性疾病 (MISC) 中的作用.
综合新知识,更新对新旧CSS的理解.

主要成果:

随着COVID-19大流行,细胞因子风暴综合征 (CSS) 的可见性和研究显著增加.
儿童多系统炎症疾病 (MISC) 已被确定为一种新的免疫媒介疾病.
持续的研究已经扩大了对各种CSSs病理生理学的理解.

结论:

由于快速的进展,需要更新关于细胞因子风暴综合征 (CSSs) 的资源.
COVID-19大流行和MISC强调了免疫媒介疾病的动态性质.
这项工作旨在为研究人员和临床医生巩固有关CSS的当前知识.

关键词:

细胞因子释放综合征细胞因子释放综合征细胞因子风暴综合征细胞因子风暴综合征血细胞性淋巴细胞细胞分裂.巨细胞激活综合征是什么

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