解释尿液中度:尿液稀释的影响和收集时间
Adrijana Oblak1, Maša Hribar2,3, Hristo Hristov2
1Division of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.
European journal of clinical nutrition
|August 8, 2024
概括
尿液度 (UIC) 的解释需要谨慎,因为尿液稀释和收集时间. 包括尿蛋白 (U-Cr) 测量和调整孕妇和年轻人改善了摄入量评估.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 公共卫生 公共卫生
背景情况:
- 尿中度 (UIC) 的中位数是估计人口摄入量的标准.
- 解释UIC值可能因尿液水化水平的变化而复杂.
研究的目的:
- 评估尿液稀释和采样时间对UIC测量的影响.
- 评估与肌素比率 (I/Cr) 的有用性,以更准确地估计摄入量.
主要方法:
- 收集了772名成年人的尿样,分为三个组:国家代表性,生育年龄的妇女和孕妇.
- 测量UIC和尿蛋白 (U-Cr) 来计算I/Cr.
- 应用了U-Cr切线 (0.226 g/L) 来识别和排除稀释样品.
- 分析了样本采集时间对UIC的影响.
主要成果:
- 各组的UIC值中位数各不相同 (例如,国家代表的UIC值为91.8μg/L,生育年龄妇女的UIC值为58.3μg/L).
- 在排除稀释样本后,调整后的UIC中位数和I/Cr比率显示了不同的值,突出显示了稀释的影响.
- 在生育年龄的妇女中,尿样采集时间显著影响了UIC,在当天晚些时候采集的样本中值较低.
结论:
- 尿路检测结果需要仔细解释,考虑到尿液稀释和采集时间.
- 结合U-Cr测量和应用校正,特别是对于孕妇和年轻成年人,提高了对摄入量评估的准确性.
- 建议在特定人群中为单点尿样采集早晨样本.
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