菌原发性和机会性病原体:一个生态视角
Sybren de Hoog1,2,3,4,5, Chao Tang1,3, Xin Zhou1,6
1RadboudUMC-CWZ Centre of Expertise for Mycology, 6525GA Nijmegen, The Netherlands.
FEMS microbiology reviews
|August 9, 2024
概括
的原发性病原性是一种有意识的策略,而不是简单的机会主义. 菌类通过在宿主之间传播进化,极端耐受性有助于适应新的环境和宿主.
科学领域:
- 菌类学 菌类学是指菌类学.
- 病变的发生和发病.
- 进化生物学 进化生物学
背景情况:
- 脊椎动物的真菌病原性通常被视为机会主义,依赖宿主组织生存.
- 主要的真菌病原体代表了一种有意识的物种健康策略,与机会性感染不同.
研究的目的:
- 将真菌原发性病原性重新定义为战略适应.
- 根据宿主相互作用和传播,区分机会性和原发性真菌病原体.
- 探索真菌病原性策略的进化影响.
主要方法:
- 对真菌生命周期和宿主-病原体相互作用的概念分析.
- 对现有关于真菌病原和演变的文献的审查.
- 菌类病原性类型的定义和分类.
主要成果:
- 初级致病性是一种有意识的策略,其中宿主有助于真菌健康.
- 机会主义涉及无传染的偶然生存,阻碍了真菌的进化.
- 主要病原体按传染方式进行分类:环境传染 (病原性) 或宿主传染 (流行性).
- 极端耐受性促进了从机会性致病性转变为初级致病性的转变,因为它可以在新的中生存.
结论:
- 菌病原性是一种进化的策略,不仅仅是机会主义的.
- 传播方式决定了进化潜力和疾病模式 (病原病与流行病).
- 环境适应性,特别是极端耐受性,是真菌过渡到初级致病性的关键.
更多相关视频
06:58Author Spotlight: Evaluation of Entomopathogenic Fungi in Wild Monochamus alternatus Populations for Biocontrol Applications in Forest Wood Borers
Published on: September 29, 2023
694
08:48Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
Published on: March 19, 2019
6.9K
相关概念视频
Skin Diseases and Disorders
3.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.7K
The Roles of Bacteria and Fungi in Plant Nutrition
35.2K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
35.2K
Infection
7.8K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.8K
Pneumonia I: Introduction
216
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
216
Epiphytes, Parasites, and Carnivores
13.0K
Plants often form mutualistic relationships with soil-dwelling fungi or bacteria to enhance their roots’ nutrient uptake ability. Root-colonizing fungi (e.g., mycorrhizae) increase a plant’s root surface area, which promotes nutrient absorption. While root-colonizing, nitrogen-fixing bacteria (e.g., rhizobia) convert atmospheric nitrogen (N2) into ammonia (NH3), making nitrogen available to plants for various biological functions. For example, nitrogen is essential for the...
13.0K
Ecological Succession
17.2K
Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...
17.2K
