相关实验视频

Updated: Jun 17, 2025

Mass Spectrometric Analysis of Glycosphingolipid Antigens
13:09

Mass Spectrometric Analysis of Glycosphingolipid Antigens

Published on: April 16, 2013

16.6K

基于质谱学的结构特异性N-Glycoproteomics和生物医学应用

Ming Bi, Zhixin Tian

    Acta biochimica et biophysica Sinica
    |August 9, 2024
    PubMed
    概括

    结合N的糖化,一种复杂的蛋白质修饰,产生多样化的糖结构. 先进的技术使N-糖蛋白的特定位置和结构分析成为可能,这对于了解疾病至关重要.

    关键词:
    生物医学应用程序葡萄糖蛋白质组学药物葡萄糖酶化是什么? 葡萄糖酶化是什么?质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量结构特定的结构特定的结构

    更多相关视频

    The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides08:37

    The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides

    Published on: November 2, 2021

    2.2K
    Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments10:59

    Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

    Published on: February 7, 2025

    953

    相关概念视频

    Peptide Identification Using Tandem Mass Spectrometry01:33

    Peptide Identification Using Tandem Mass Spectrometry

    Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
    This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
    6.4K
    Mass Spectrometry: Complex Analysis01:21

    Mass Spectrometry: Complex Analysis

    Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
    GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
    737
    MALDI-TOF Mass Spectrometry01:19

    MALDI-TOF Mass Spectrometry

    Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.
    Matrix-assisted laser desorption ionization (MALDI) is a commonly...
    4.7K
    Proteomics01:33

    Proteomics

    A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
    Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
    7.3K