评估患有类风湿性关节炎的50岁以上妇女的疲劳:使用FACIT-F尺度进行全面的病例对照研究
Lidia Valencia-Muntalà1, Carmen Gómez-Vaquero1, Laura Berbel-Arcobé1
1Department of Rheumatology, IDIBELL-Hospital Universitari de Bellvitge, University of Barcelona, Barcelona, Spain.
Frontiers in medicine
|August 9, 2024
概括
疲劳显著影响着50岁以上的风湿性关节炎 (RA) 的西班牙妇女,比对照群更为普遍和严重. 疾病活动和健康状况是关键的影响因素.
科学领域:
- 类风湿病学 类风湿病学
- 临床医学 临床医学
- 流行病学 流行病学
背景情况:
- 疲劳是风湿性关节炎 (RA) 患者常见但尚未研究的并发症,特别是在先进的生物治疗时代.
- 有限的病例控制研究存在于RA群体的疲劳患病率及其决定因素.
研究的目的:
- 通过使用慢性疾病治疗-疲劳 (FACIT-F) 尺度的功能评估,评估50岁以上的患有RA的西班牙妇女的疲劳 prevalence.
- 探索疲劳和RA相关变量之间的关联.
- 确定影响这一人口群体疲劳的主要因素.
主要方法:
- 一项涉及191名50岁以上的西班牙妇女的病例控制研究,符合RA和年龄匹配对照的ACR 2010标准.
- 使用FACIT-F尺度,SF-12问卷和RA特定临床措施进行评估.
主要成果:
- 在 RA 患者中,疲劳的发生率明显高于对照组 (61%),而不是对照组 (37%,p < 0.001).
- 关节炎患者报告FACIT-F平均得分较低,表明疲劳严重程度较高.
- 多变量分析显示,疲劳受到疾病活动 (RAPID 3),精神/身体健康 (SF-12) 和年龄的显著影响,解释了81.7%的差异.
结论:
- 疲劳在50岁以上的RA妇女中非常普遍和严重,与疾病活动,残疾和生活质量下降有关.
- 系统的疲劳评估和有针对性的干预措施在临床实践中至关重要.
- 建议进一步研究为这个人口群体量身定制的干预措施.
相关概念视频
Fatigue
178
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
178
Assessment of the Cardiovascular System I: Subjective Data
293
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
293
Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K
Physical Assessment of the Respiratory Tract II: Palpation
286
Physical assessment of the respiratory tract is critical in identifying potential health issues. One key component of this assessment is palpation, a technique healthcare providers use to assess the body for abnormalities. This content explores the method of palpation in evaluating the respiratory tract, focusing on thoracic palpation and tactile fremitus.
Thoracic Palpation
Thoracic palpation detects tenderness, masses, lesions, respiratory excursions, and vocal fremitus. The nurse assesses...
Thoracic Palpation
Thoracic palpation detects tenderness, masses, lesions, respiratory excursions, and vocal fremitus. The nurse assesses...
286
Fatigue Strength of Concrete
179
Fatigue, in the context of materials science and engineering, refers to the weakening or failure of a material caused by repeatedly applied loads, even if these loads are below the strength limit of the material. Fatigue strength in concrete is a critical property that influences its durability and longevity. Concrete can fail in two ways due to fatigue. Static fatigue or creep rupture occurs under a constant load or one that increases slowly. The other failure mode is due to cyclical or...
179
Assessment of the Gastrointestinal System II: Health Perception Pattern
87
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
87


