审查内支气管治疗的现状和未来状况
Joyce W Y Chan1, Ivan C H Siu1, Aliss T C Chang1
1Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
Annals of translational medicine
|August 9, 2024
概括
肺癌查发现了更多的早期疾病,增加了对肺上腺素节约疗法的需求. 微波切除和新兴的横支气管切除技术提供了有前途的局部肺癌治疗选择.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 医疗技术 医疗技术 医学技术
背景情况:
- 多焦点肺癌的发病率不断增加,需要使用节省肺辅酶的疗法.
- 肺癌查的进步发现了更多的早期癌症,将重点转向局部治疗.
- 越来越多的患者无法接受传统手术,这推动了对替代疗法的需求.
研究的目的:
- 审查用于局部肺癌治疗的跨支气管治疗方法的进展.
- 探索新兴技术和未来的应用在轻微侵入性肺癌护理.
- 突出微波除的潜力和在治疗肺部瘤的新补充剂.
主要方法:
- 对跨支气管疗法和相关技术的当前文献的综述.
- 对微波除的早期和中期结果的分析.
- 讨论诸如机器人支气管镜和纳米颗粒等辅助方法,以提高切除精度.
- 探索新兴的能量模式 (蒸汽,脉冲电场,光动力学疗法) 和内药物 (免疫疗法,基因疗法,CAR T细胞).
主要成果:
- 微波切除证明了局部肺癌的早期和中期结果是有希望的.
- 辅助技术提高了跨支气管切除的精度和效率.
- 新能源和内毒剂正在进行密集调查.
- 在临床前和一些临床研究中,结合疗法与切除疗法显示出协同作用的abscopal效应.
结论:
- 跨支气管疗法,特别是微波切除,正在发展成为局部肺癌治疗的关键工具.
- 技术进步和新型治疗剂正在扩大微创肺癌管理的可能性.
- 未来的横支气管治疗方法可能涉及结合切除与免疫疗法,基因疗法和其他创新药物,以提高疗效.
相关概念视频
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
182
Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
182
COPD: Management Using Bronchodilators and Corticosteroids
192
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
192
Drugs Used in Lower Respiratory Disorders: Overview
383
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
383
Chronic Obstructive Pulmonary Disease-V: Management
2.5K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
2.5K
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
147
Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
147
Chronic Obstructive Pulmonary Disease-V: Nursing Management
3.7K
Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment
Assessment
3.7K


