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相关概念视频

Ventilatory Modes01:14

Ventilatory Modes

99
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
99

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相关实验视频

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Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs
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一个可调节体积的人工子宫,用于极其早产的婴儿.

Jan Heyer1, Franziska Schubert1, Alexander L Seitz1

  • 1Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen University and University Hospital, Aachen, Germany.

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概括

通过开发人工子宫,这项通往生命的桥梁技术通过为器官成熟提供生理液态环境来支持极度早产的婴儿. 该系统表现出适应胎儿生长的能力,并保持长达7天的稳定条件.

关键词:
可调节的袋.人造胎囊是一种人工的胎囊.人工子宫的人工子宫极度早产的婴儿 非常早产的婴儿围产期生命支持器的生命支持.

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科学领域:

  • 新生儿医学 新生儿医学
  • 生物医学工程 生物医学工程
  • 发育生物学是发展生物学.

背景情况:

  • 每年有超过1300万名婴儿早产,早产导致全球090万例死亡.
  • 极度早产的婴儿 (妊娠年龄<28周) 面临器官衰竭和由于不成熟的特定疾病.
  • 对于极端早产的现有治疗方法在预防死亡率和长期并发症方面取得了有限的成功.

研究的目的:

  • 开发和评估人工子宫和胎盘技术,作为极度早产新生儿的生命桥梁解决方案.
  • 创建一个支持在液态环境中生理器官成熟的系统,模仿子宫内条件.
  • 设计一种可适应的人造子宫,能够在一定的时间内容纳胎儿生长.

主要方法:

  • 设计了一个人工子宫系统,可调整内囊体积 (3.67.0 L),使用室间的液体去除.
  • 开发了一种过和消毒系统,以管理代谢废物并防止脂洗.
  • 在体外测试进行了7天,以评估温度稳定性 (36.8°C ± 0.3°C) 和压力完整性.

主要成果:

  • 人造子宫保持了稳定的温度36.8°C±0.3°C,没有压力损失7天.
  • 该系统证明了有效的过,消毒和预防脂洗.
  • 人造子宫的体积可变性足以支持4周的生理生长.

结论:

  • 人造子宫技术显示出作为极度早产婴儿的桥梁解决方案的承诺.
  • 该系统适应胎儿生长和维持生理条件的能力是一个重要的进步.
  • 这项技术的进一步开发可以减少与早产相关的死亡率和发病率.