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相关概念视频

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.7K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

206
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
206
Skin Cancer01:30

Skin Cancer

4.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.0K
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

4.4K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.4K

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Updated: Jun 17, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

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在皮肤神经炎中发生的结症.

Srijana Davuluri1, Lorinda Chung2, Christian Lood3

  • 1Stanford School of Medicine Division of Rheumatology.

Current opinion in rheumatology
|August 9, 2024
PubMed
概括

皮肤肌炎中的毒症涉及沉积物引起发病. 早期疾病控制和了解像中性粒细胞激活这样的新途径是管理这种疾病的关键,特别是在青少年病例中.

科学领域:

  • 类风湿病学 类风湿病学
  • 皮肤病学 皮肤病学
  • 免疫学 免疫学 免疫学

背景情况:

  • 炎,以不溶性化合物沉积为特征,影响多达75%的青少年皮肤肌炎患者和20%的成人皮肤肌炎患者.
  • 这种疾病对患者的发病率有显著的贡献,但其完整的发病因子仍然不完全理解.

研究的目的:

  • 审查最新的关于皮肤肌肉炎病原和治疗化症的文献.
  • 突出最近在了解驱动化发展的机制方面的进展.

主要方法:

  • 关于皮肤肌肉炎相关的结症的最近研究的文献综述.
  • 对观察性队列研究和专注于病原和治疗的病例系列的分析.

主要成果:

  • 长时间的炎症和血管功能障碍与结症有关.
  • 新出现的证据表明,中性粒细胞激活和线粒体功能障碍是潜在的致病途径.
  • 早期诊断和疾病活动控制对于预防青少年皮肤肌炎中炎至关重要.

结论:

  • 炎是皮肤肌炎的常见和衰弱的并发症.
  • 虽然手术切除是息治疗的主要支柱,但其他治疗方法的证据有限.

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Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
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  • 需要进一步的研究来充分阐明病原体和开发有效的疗法,局部硫酸盐和JAK抑制剂显示出有前途.