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Updated: Jun 17, 2025

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes
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Published on: August 24, 2021

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INPP4B通过PIKfyve和TRPML-1-介导的溶酶体外细胞分裂促进PDAC的攻击性

Golam T Saffi1, Lydia To1, Nicholas Kleine1

  • 1Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada.

The Journal of cell biology
|August 9, 2024
PubMed
概括

在胰腺癌细胞中INPP4B的过度表达通过增强 lysosomal exocytosis促进了入侵. 这项研究揭示了涉及INPP4B,PIKfyve和TRPML-1在胰腺管腺癌进展中的新途径.

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