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微流体可编程策略用于通道和流量
Yongxian Song1, Yijiang Zhou2, Kai Zhang3
1School of Electronic Engineering, Nanjing Xiaozhuang University, Nanjing, Jiangsu 211171, China. soyox@163.com.
Lab on a chip
|August 9, 2024
概括
可编程的微流体提供精确的流体控制使用微和微. 这些先进的系统提高了生物医学研究和药物查的自动化和可访问性.
科学领域:
- 微流体学 微流体学
- 生物技术是生物技术.
- 工程 工程师 工程师 工程师
背景情况:
- 微流体技术可以在微尺度上精确地处理流体.
- 传统的微流体系统往往缺乏灵活性和易用性.
- 正在出现可编程策略来克服这些局限性.
研究的目的:
- 审查可编程微流体,包括微通道设计和液体特性操纵.
- 探索各种微和微类型,用于精确的流体控制和自动化.
- 讨论数字化,多重复合和基于混合器的微流体应用,包括SlipChip技术和模块化组装.
主要方法:
- 审查微技术 (电动力学,液压,,相变,检查).
- 分析微型设计 (被动,主动).
- 探索数字微流体,复合,微混合器,SlipChip和模块化组装策略.
主要成果:
- 微和微对于精确的流体控制和微流体设备中的自动化至关重要.
- 数字化,多重化和基于混合器的微流体利用物理力量进行复杂的流体操纵.
- 创新的模块化设计提高了系统的重新配置性,灵活性和用户友好性.
结论:
- 可编程微流体学为各种应用提供先进的流体控制.
- 这些技术越来越多地被整合到医疗设备和生物分析工具中.
- 增强的用户友好性和可访问性为研究和工业更广泛采用铺平了道路.
相关概念视频
Steady Flow of a Fluid Stream
Consider a control volume, such as a pipe with solid boundaries, through which fluid flows and changes direction due to the impulse exerted by the resulting force from the pipe walls. In steady flow, the mass of fluid entering the control volume at a given time, t, with velocity v1, is equal to the mass leaving after infinitesimal time dt, with velocity v2.
During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...
During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...
Stream Function
In two-dimensional incompressible fluid flow, the continuity equation is essential for ensuring mass conservation, meaning that any change in fluid entering or exiting a region is balanced by a corresponding change elsewhere. For incompressible flow, where density remains constant, this requirement simplifies to the condition that the divergence of the velocity field must be zero. Mathematically, this is expressed as,
Uniform Depth Channel Flow
Uniform depth channel flow keeps fluid depth consistent along channels such as irrigation canals. In natural channels, such as rivers, approximate uniform flow is often assumed. This condition occurs when the channel’s bottom slope matches the energy slope, balancing potential energy lost from gravity with head loss due to shear stress. This balance prevents depth changes along the channel length, resulting in a steady, uniform flow.Uniform flow in open channels with a constant cross-section...
Uniform Depth Channel Flow: Problem Solving
To calculate the flow rate for a trapezoidal channel, first, identify the bottom width, side slope, and flow depth of the channel. The cross-sectional area (A) corresponding to the depth of flow (y), channel bottom width (B), and side slope (θ) is determined by:Next, calculate the wetted perimeter, which includes the bottom width and the sloped side lengths in contact with the water. Using the values of the cross-sectional area and the wetted perimeter, determine the hydraulic radius by...
Gradually Varying Flow
Gradually varying flow (GVF) in open channels describes situations where water depth changes slowly along the channel due to factors like non-uniform bed slope, channel shape variations, or obstructions. This flow type occurs when the depth adjusts gradually to balance gravitational forces, shear forces, and energy requirements, resulting in a low rate of depth change.Characteristics of Gradually Varying FlowGVF is commonly observed in natural streams, rivers, and canals, where flow depth...
Rapidly Varying Flow
Rapidly varying flow (RVF) in open channels is characterized by abrupt changes in flow depth over a short distance, with the rate of depth change relative to distance often approaching unity. These flows are inherently complex due to their transient and multi-dimensional nature, making exact analysis difficult. However, approximate solutions using simplified models provide valuable insights into their behavior.Key Features of Rapidly Varying FlowRVF is commonly observed in scenarios involving...

