种族和种族与间歇性肺病的关联以及系统性硬化症患者的医疗保健利用情况
Ann-Marcia C Tukpah1, Jonathan A Rose1, Diane L Seger2
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Rheumatology (Oxford, England)
|August 9, 2024
概括
在全身性硬化症-间歇性肺病 (SSc-ILD) 中存在种族和民族差异. 少数群体更早出现,急诊室访问率更高,突出了SSc-ILD结果的关键差异.
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 健康差异 在健康上的差异
背景情况:
- 系统性硬化症 (SSc) 和其并发症间歇性肺病 (ILD) 在表现和结果上表现出已知的种族和民族差异.
- 之前对这些差异的研究受到研究队伍缺乏多样性的限制.
研究的目的:
- 在SSc患者中调查ILD患病率的种族和民族差异.
- 检查跨种族/种族群体SSc诊断和ILD诊断之间的时间间隔的差异.
- 评估与SSc-ILD相关的急诊室 (ED) 访问和住院率的种族/民族差异.
主要方法:
- 使用纵向健康记录分析了756名SSc患者的队列.
- 使用后勤回归模型来确定共变量与ILD之间的关联,以及SSc-ILD诊断时的年龄.
- 补充的日志回归模型被用于分析医疗保健结果,包括急救诊所和住院治疗.
主要成果:
- 与白人患者相比,亚洲患者的ILD患病几率增加 (OR,2.60).
- 与白人患者相比,西班牙裔和黑人/非洲裔美国患者在较年轻时被诊断出SSc-ILD.
- 黑人/非洲裔美国患者在SSc之前更有可能被诊断为ILD,并且经历了较短的SSc-ILD间隔 (3个月).
- 黑人/非裔美国人和西班牙裔患者的急救诊所访问率显着更高.
结论:
- 种族和民族背景与发展SSc-ILD的几率不同有关.
- 少数种族和民族群体经历SSc-ILD的早期呈现.
- 在SSc-ILD的少数患者中,医疗保健利用的差异,特别是更高的ED访问率,是显而易见的.
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