肥胖和之间的关系:通过元分析进行系统审查
Yu-Xuan Li1, Wang Guo1, Ruo-Xia Chen1
1Clinical Medical School, Dali University, Dali, China.
PloS one
|August 9, 2024
概括
与健康人相比,患者的肥胖患病率较高. 这一元分析强调了在管理中对肥胖的临床关注和进一步研究它们之间的关系的需要.
科学领域:
- 神经学与公共卫生
- 代谢障碍 研究 研究 代谢障碍
- 流行病学研究 流行病学研究
背景情况:
- 和肥胖之间的关联是正在进行的科学辩论的主题.
- 了解这种关系对于全面的患者护理和公共卫生战略至关重要.
研究的目的:
- 通过元分析系统地检查和肥胖之间的相关性.
- 综合现有证据,分析患有的人群中肥胖患病率的现有证据,与健康对照对比.
主要方法:
- 遵守PRISMA系统审查和元分析指南.
- 在Cochrane Library,PubMed,Web of Science和Embase数据库中进行全面的文献搜索.
- 包括符合特定标准的病例控制,队列,随机对照试验和横截面研究,并使用RevMan 5.3.3进行元分析.
主要成果:
- 分析了17项涉及5329名患者和480,837名健康对照者的研究.
- 一个固定效应模型显示,患者中肥胖的流行率较高,具有统计学意义 (OR = 1.28,95% CI: 1.20-1.38,p<0.01).
- 没有观察到显著的异质性 (p = 0.01,I2 = 49%).
结论:
- 与普通人群相比,患者对肥胖的倾向更大.
- 对后肥胖的临床关注是有必要的.
- 需要进一步进行大规模的前性研究,以探索肥胖症作为伴随性疾病或的潜在触发因素.
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