西NK

Yantong Guo1, Jianting Xu2, Yiyang Jia3

  • 1Cancer Institute, First Hospital of Jilin University, Changchun, 130012, PR China.

概括

亚西化物通过抵消转化生长因子-β (TGF-β) 免疫抑制来增强自然杀手 (NK) 细胞的抗瘤活性. 这种化合物保留NK细胞的线粒体功能,为癌症免疫治疗提供了一种新的策略.

相关概念视频

Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
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