静脉血栓塞栓症患者的焦虑:前性队列研究中的量化和风险因素
Daniel Steiner1, Stephan Nopp2, Timothy Hoberstorfer2
1Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria. Electronic address: https://twitter.com/DanielSteinerMD.
Journal of thrombosis and haemostasis : JTH
|August 9, 2024
概括
大多数患有静脉血栓塞栓症 (VTE) 的患者在诊断后经历了减少的焦虑. 然而,一些人,尤其是患有深静脉血栓症 (DVT) 的老年女性,可能会感到焦虑增加,强调需要有针对性的心理健康支持.
科学领域:
- 医学研究 医学研究
- 临床心理学 临床心理学
- 心血管健康的心血管健康
背景情况:
- 静脉血栓塞栓症 (VTE) 可以导致心理痛苦,但与身体影响相比,心理健康后果仍未得到充分研究.
- 焦虑是VTE事件后的一个常见的心理后果.
- 现有的研究尚未完全阐明与VTE后焦虑轨迹相关的临床因素.
研究的目的:
- 为了量化患者在急性VTE事件后的焦虑水平.
- 在3个月的随访中确定与焦虑相关的临床特征.
- 根据焦虑的变化随着时间的推移,探索不同的患者群.
主要方法:
- 潜在的队列研究设计包括急性深静脉血栓塞 (DVT) 和/或肺栓塞的患者.
- 排除标准:癌症,怀孕或产后期.
- 使用患者报告结果测量信息系统 (PROMIS) 简体表格8a进行焦虑评估,通过多变量线性回归分析T分数.
主要成果:
- 分析了257名患者 (38.5%为女性,中位数年龄为54.1岁) 的队列.
- 平均焦虑T分数从基线 (51.03) 降低到3个月的随访 (46.74),P < .001.
- 在23.7%的患者中观察到焦虑的增加,与女性性别,年龄较小 (≤45岁) 和基线焦虑有关. 患有DVT的老年女性表现出增加焦虑的趋势.
结论:
- 虽然VTE后的焦虑通常会减少,但显著的少数人会经历症状恶化.
- 女性性别,年龄较大,更高的基线焦虑和特定的静脉瘤类型 (DVT) 与3个月的焦虑增加有关.
- 这些发现强调了监测和解决VTE患者的心理健康的重要性,特别是特定的人口群体.
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