由于其他原因导致的SARS-CoV-2相关的外原流水和外原流水之间的区别
Didem Kazan1,2, Defne Özkoca3, Nazlı Dizen Namdar1
1Kutahya Health Science University, Evliya Celebi Training and Research Hospital, Dermatology and Venerology Clinic, Kutahya, Turkey.
Dermatology practical & conceptual
|August 9, 2024
概括
与SARS-CoV-2相关的电位排泄症 (CATE) 与电位排泄症 (TEDOC) 的其他原因相比,呈现出更快的发型脱发. 皮肤镜检测结果,如空卵泡口和黄色点,有助于诊断CATE.
科学领域:
- 皮肤病学 皮肤病学
- 三学是指三学的学科.
- 传染病流行病学 传染病流行病学
背景情况:
- 泰洛根流水 (TE) 是一种常见的非伤性脱发症.
- 在SARS-CoV-2感染后的患者中经常观察到TE.
研究的目的:
- 调查SARS-CoV-2相关TE (CATE) 的人口,皮肤镜和实验室特征.
- 根据这些特征,将CATE与来自其他原因的TE (TEDOC) 进行比较.
主要方法:
- 对92名被诊断患有TE的成年患者进行了回顾性病例控制研究 (2022年4月至6月).
- 患者分为CATE (在3个月内呈阳性SARS-CoV-2 PCR) 和TEDOC组.
- 收集的数据包括人口统计,疾病持续时间,全身状况,皮肤镜检查和实验室结果.
主要成果:
- 在56.5%的患者中发现了CATE;在44.5%的患者中发现了TEDOC.
- 从SARS-CoV-2感染到脱发的平均时间为64.8天,明显短于TEDOC (P=0.003).
- 皮肤镜检查显示,CATE的空卵泡开口和黄色点的比率更高,TEDOC的短发再生率更高 (所有人P<0.001).
结论:
- CATE的特点是感染后的快速脱发,比经典TE更早发生.
- 皮肤镜检测结果可以帮助区分CATE与TEDOC.
- 早期诊断和管理CATE至关重要.
相关概念视频
01:06Multipotency and Niche of Bulge Stem Cell
3.5K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
3.5K
02:15Replicative Cell Senescence
3.6K
Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds...
3.6K