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Updated: Jun 17, 2025

Initial Evaluation of Antibody-conjugates Modified with Viral-derived Peptides for Increasing Cellular Accumulation and Improving Tumor Targeting
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作为抗体-药物结合物的单域抗体:从承诺到实践-系统性审查

Víctor Manuel Medina Pérez1, Marta Baselga1, Alberto J Schuhmacher1,2

  • 1Molecular Oncology Group, Instituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.

Cancers
|August 10, 2024
PubMed
概括

单域抗体 (VHHs) 显示出下一代抗体-药物联合体 (ADCs) 的前景. 它们的小尺寸和稳定性提高了瘤的透率,降低了毒性,可能提高了癌症治疗的疗效和安全性.

关键词:
这是一个ADCADC ADC.这就是HCAbb.这就是VHH VHH.抗体药物合物 抗体药物合物纳米体是一个纳米体.sdAb sdAb 在线阅读一个单链变量片段的变量片段.单域抗体对合物 单域抗体对合物小格式抗体药物联合体

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