高食铁对的脂肪沉积和肠道微生物群的影响
Ting Yang1,2, Shihao Chen1,2, Lingling Qiu1,2
1College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.
Animals : an open access journal from MDPI
|August 10, 2024
概括
食补充铁可以通过改善肠道微生物群平衡来减少的过度脂肪沉积. 这一发现为防止家禽生产中脂肪积累提供了新的策略.
科学领域:
- 动物科学动物科学
- 营养科学 营养科学
- 微生物学 微生物学
背景情况:
- 现代家禽养殖旨在满足消费者的需求,但导致了的过度脂肪沉积.
- 高脂肪饮食可能会对的健康产生负面影响,导致脂肪积累增加和肝损伤.
- 了解食成分如铁在减轻这些影响中的作用对于家禽业至关重要.
研究的目的:
- 为了研究食补充铁对丝鸟黑骨脂肪沉积和肠道微生物群的影响.
- 为了确定铁能否抵消高脂肪饮食对健康和新陈代谢的负面影响.
- 探索铁,脂肪沉积和肠道微生物组成之间的关系.
主要方法:
- 丝鸟黑骨被食控制饮食,高脂肪饮食 (HFD) 或HFD含500毫克/公斤铁 (HFDFe500) 28天.
- 评估了生长性能,肝脏和血清脂肪沉积 (油红色O和HE染色),以及肝损伤.
- 用16S rDNA测序分析了肠道微生物组成,使用PICRUSt.进行了功能预测.
主要成果:
- 高脂肪饮食显著增加了肝脏和血清脂肪沉积和肝脏损伤.
- 食补充铁减少了高脂肪饮食养的脂肪沉积和减轻肝损伤.
- 高脂肪饮食导致肠道微生物不平衡,而高铁饮食可以逆转;补充铁会影响微生物代谢途径,并与特定的细菌类 (Firmicutes,Actinobacteriota) 相相关.
结论:
- 食补充铁 (500 mg/kg) 有效地减少的脂肪沉积和肝损伤,即使在高脂肪条件下.
- 铁会影响肠微生物群的组成和功能,这表明有调节脂肪沉积的机制.
- 补充铁是一种有希望的策略,通过调节肠道微生物群来防止家禽过度脂肪沉积.
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