在COVID-19大流行期间血清25-氧维生素D水平上升
Witt Durden1,2, Shady Ezaldin1, Jessica Amos1,2
1Charleston Area Medical Center, Institute for Academic Medicine, 3200 MacCorkle Ave SE, Charleston, WV 25304, USA.
Nutrients
|August 10, 2024
概括
在COVID-19大流行期间,维生素D补充剂的摄入量显著增加,导致患者的血清25-氧维生素D水平升高. 这凸显了在危机期间需要基于证据的健康信息的需要.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 营养科学 营养科学
背景情况:
- 随着COVID-19大流行,已建立的治疗方案中出现了真空,促使人们探索实验性疗法,如高剂量维生素D.
- 由于在线讨论,公众对维生素D在打击COVID-19中的潜在作用的兴趣急剧增加.
研究的目的:
- 为了调查COVID-19大流行期间患者血清25-氧维生素D水平的变化.
- 分析关于补充维生素D的公共话语对患者血清水平的影响.
主要方法:
- 查尔斯顿地区医疗中心 (CAMC) 的35,556名患者的回顾性队列分析.
- 在大流行前 (2019年) 和大流行 (2021年) 期间,血清25-基维生素D水平的比较.
主要成果:
- 平均血清25-基维生素D水平从2019年的31±15 ng/mL显著增加到2021年的37±21 ng/mL (p ≤0.001).
- 在2021年,更高比例的患者患有维生素D水平升高:>100 ng/mL (1.6%对比0.2%),75-100 ng/mL (4.6%对比1.2%),50-75 ng/mL (16.0%对比8.4%) (p ≤0.001).
结论:
- 观察到的血清维生素D水平的增加表明,在大流行期间,补充剂的使用量增加.
- 这一趋势强调了传播基于证据的公共卫生信息,以减轻卫生危机期间的健康风险至关重要.
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