单次高剂量维生素D补充对超级高山跑后心脏损伤和铁代谢变化的影响:双盲随机对照试验
Błażej Stankiewicz1, Jan Mieszkowski2,3, Andrzej Kochanowicz2
1Department of Theory and Methodology of Physical Education and Sport, Faculty of Health Sciences and Physical Education, Kazimierz Wielki University, 85-064 Bydgoszcz, Poland.
Nutrients
|August 10, 2024
概括
维生素D3补充剂并没有改变大多数超级马拉松诱导炎症和铁代谢变化的标志物. 然而,它确实影响了红色素 (EPO) 和心脏热素T (cTnT) 水平,这表明它可能在减轻心脏损伤方面发挥作用.
科学领域:
- 运动生理学 运动生理学
- 营养科学 营养科学
- 心脏病学 心脏病学
背景情况:
- 运动引起的炎症会影响铁的新陈代谢.
- 维生素D3对超级马拉松引起的心脏损伤和铁代谢的影响尚不清楚.
- 维生素D3具有抗炎性质.
研究的目的:
- 研究维生素D3补充剂对超级马拉松引起的心脏损伤和铁代谢的影响.
- 为了检查维生素D3,炎症和耐力运动员的心脏生物标志物之间的关系.
主要方法:
- 在超级马拉松之前,35名半业余跑者被分为维生素D3 (150,000 IU) 或安慰剂组.
- 测量了铁,肝素 (HPC),费里丁 (FER),红红 (ERFE),红蛋白 (EPO),新丁 (NPT) 和心脏素T (cTnT) 的血清水平.
- 在比赛后立即评估生化标志物.
主要成果:
- 超级马拉松跑步显著增加了所有参与者的ERFE,EPO,HPC,NPT和cTnT水平.
- 维生素D3补充剂与超级马拉松跑步有显著的相互作用,特别是影响EPO和cTnT水平.
- 观察到基线费里和运行后的红之间存在相关性;维生素D3改变了肝素水平.
结论:
- 超级马拉松跑步显著影响EPO/ERFE/HPC轴和心脏生物标志物.
- 一次高剂量的维生素D3主要影响EPO水平,这与心脏损伤标志物cTnT的减少相关.
- 需要进一步的研究来阐明维生素D3在耐力运动员中的具体机制.
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