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精神分裂症患者减肥手术的结果
Inka Miñambres1,2,3, Miguel Ángel Rubio-Herrera4,5, Joana Nicolau6
1Servicio de Endocrinología, Hospital de La Santa Creu i Sant Pau, 08041 Barcelona, Spain.
Nutrients
|August 10, 2024
概括
减肥手术 (BS) 对精神分裂症 (SZ) 或精神分裂情绪障碍 (SZA) 患者是安全的. 减肥和并发症缓解与对照组相似,精神病状况没有恶化.
科学领域:
- 代谢和腹部手术 代谢和腹部手术
- 精神疾病 精神疾病
- 伴发病性疾病管理
背景情况:
- 精神分裂症 (SZ) 或精神分裂情绪障碍 (SZA) 患者的减肥手术 (BS) 的结果没有得到充分记录.
- 关于BS在这种特定患者群体中的安全性和有效性的数据有限.
研究的目的:
- 分析BS对被诊断为精神分裂症或精神分裂情绪障碍患者的影响.
- 为了比较精神病患者和对照患者之间的减肥和并发症缓解率.
主要方法:
- 一个多中心,回顾性病例控制研究,涉及20名患有SZ或SZA的患者,他们接受了BS.
- 包括80个没有精神病并发症的匹配对照.
- 临床和生化数据是在手术前和手术后的60个月内收集的.
主要成果:
- 在患者和对照组之间没有观察到体重减轻的显著差异.
- 大多数并发症的缓解率相似,除了高血压,从3年开始,BS组的缓解率较低.
- 在随访期间,没有30天死亡率和精神病药物负担的变化.
结论:
- 减肥手术对于精心挑选的精神分裂症患者来说是一个安全有效的选择.
- 这种程序似乎不会对精神疾病的发展产生负面影响.
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